VITT-like Monoclonal Gammopathy of Thrombotic Significance
Identifican una forma crónica de trombosis resistente a anticoagulantes asociada a anticuerpos tipo VITT, distintos a los del VITT agudo post-vacunal. Requiere tratamiento más allá de la anticoagulación.
Inmunotrombosis: un mecanismo clave en la pandemia por COVID-19
La infección por SARS-CoV-2 desencadena un proceso conocido como inmunotrombosis o tromboinflamación, entidad descrita inicialmente por Engelmann y Massber para definir la relación bidireccional entre los mecanismos de coagulación y el sistema inmune. Este mecanismo, desarrollado como un sistema de defensa del organismo para eliminar patógenos, se vuelve aberrante en el contexto de infección por COVID-19, provocando coagulopatía, endoteliopatía e inflamación, y ello favorece la microtrombosis no solo en la circulación pulmonar, sino también a nivel de diversos órganos, que puede desencadenar un fallo multiorgánico
Contraceptive Recommendations for Womenwith Immune-Mediated Inflammatory Diseases:A Delphi Consensus
Immune-mediated inflammatory diseases (IMID) are a group of disorders characterized by chronic inflammation caused by an altered immune regulation in targeted organs or systems. IMID itself could have an implied increased risk of venous thromboembolism (VTE) and this risk varies throughout the course of the disease as well as with some contraceptive methods and treatments. The aim of this study was to present some key considerations in relation to contraception in women with IMID.
EHA Guidelines on Management of Antithrombotic Treatments in Thrombocytopenic Patients With Cancer
In cancer patients, thrombocytopenia can result from bone marrow infiltration or from anticancer medications and represents an important limitation for the use of antithrombotic treatments, including anticoagulant, antiplatelet, and fibrinolytic agents.
Targeted long-read sequencing identifies and characterizes structural variants in cases of inherited platelet disorders
Autores: Ana Zamora-Cánovas, Belén de la Morena-Barrio, Ana Marín-Quílez, Cristina Sierra-Aisa, Christoph Male, Nuria Fernández-Mosteirin, María Trapero-Marugán, José Padilla, Pedro Garrido-Rodriguez, Ana Sánchez-Fuentes, Agustín Rodríguez-Alen, Pedro Luis Gómez-González, Nuria Revilla, […]
Immunothrombosis: Molecular Aspects and New Therapeutic Perspectives
Thromboinflammation or immunothrombosis is a concept that explains the existing link between coagulation and inflammatory response present in many situations, such as sepsis, venous thromboembolism, or COVID-19 associated coagulopathy.
Use of Direct Acting Oral Anticoagulants in Elderly Patients with Atrial Fibrillation: A Multicenter, Cross-Sectional Study in Spain
Non-vitamin K antagonist oral anticoagulants (NOACs) have substantially improved anticoagulation. However, data on NOAC use among elderly patients are scarce.
Platelet transcriptome analysis in patients with germline RUNX1 mutations
Verónica Palma-Barqueros, José María Bastida, María José López Andreo, Ana Zamora Cánovas, Carlo Zaninetti, Juan Francisco Ruiz-Pividal, Natalia Bohdan, José Padilla, Raúl Teruel-Montoya, Ana Marín-Quilez, Nuria Revilla, Ana Sánchez-Fuentes, Agustín […]
